Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL5095328 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL20298871 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27816908 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL28001186 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL4165306 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL377416 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL29089144 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL30528009 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL872998 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27466658 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250072457-A1 | Beverages Comprising Protein Sweeteners with Improved Taste and Mouthfeel | THE COCA-COLA COMPANY | 2025-03-06 | — | — | US | disclosed |
| EP-4456739-A1 | BEVERAGES COMPRISING PROTEIN SWEETENERS WITH IMPROVED TASTE AND MOUTHFEEL | The Coca-Cola Company (US) | 2024-11-06 | — | — | EP | disclosed |
| CN-118647282-A | Beverage comprising protein sweetener with improved taste and mouthfeel | 可口可乐公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-117750886-A | Salt-containing beverage with improved taste | 可口可乐公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4333641-A1 | BEVERAGES COMPRISING SALTS WITH IMPROVED TASTE | The Coca-Cola Company (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20240057641-A1 | Beverages Comprising Salts with Improved Taste | THE COCA-COLA COMPANY | 2024-02-22 | — | — | US | disclosed |
| WO-2023130065-A1 | BEVERAGES COMPRISING PROTEIN SWEETENERS WITH IMPROVED TASTE AND MOUTHFEEL | THE COCA-COLA COMPANY (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2022235772-A1 | BEVERAGES COMPRISING SALTS WITH IMPROVED TASTE | THE COCA-COLA COMPANY (US) | 2022-11-10 | — | — | WO | disclosed |