Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL28001186 | 1.00 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL20298871 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL5095328 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27816908 | 0.98 | PDE4A (0.79) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL25311486 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL4165306 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL29089144 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL872998 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL30528009 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 | |
| Gluconic Acid SCHEMBL27466658 | 0.96 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408317-B1 | DIETARY SUPPLEMENT | GREENTEAM HOLDINGS LTD (GB) | 2017-10-04 | — | — | EP | claimed |
| EP-2996495-A1 | CALCIUM SUPPLEMENT | Calinnova Ltd (GB) | 2016-03-23 | — | — | EP | claimed |
| US-20150201650-A1 | DIETARY SUPPLEMENT | Greenteam Holdings Limited (GB) | 2015-07-23 | — | — | US | claimed |
| WO-2014177876-A1 | CALCIUM SUPPLEMENT | CALINNOVA LTD (GB) | 2014-11-06 | — | — | WO | claimed |
| US-20120121754-A1 | Dietary Supplement | CALLINOVA LTD (GB) | 2012-05-17 | — | — | US | claimed |
| EP-2408317-A1 | DIETARY SUPPLEMENT | Calinnova Ltd (GB) | 2012-01-25 | — | — | EP | claimed |
| WO-2010106351-A1 | DIETARY SUPPLEMENT | VETAFARM EUROPE LTD (GB) | 2010-09-23 | — | — | WO | claimed |
| EP-2408317-B1 | DIETARY SUPPLEMENT | GREENTEAM HOLDINGS LTD (GB) | 2017-10-04 | — | — | EP | disclosed |
| EP-2996495-A1 | CALCIUM SUPPLEMENT | Calinnova Ltd (GB) | 2016-03-23 | — | — | EP | disclosed |
| US-20150201650-A1 | DIETARY SUPPLEMENT | Greenteam Holdings Limited (GB) | 2015-07-23 | — | — | US | disclosed |
| CN-104351679-A | Processing method of instant type carrot slices rich in zinc, calcium and magnesium | UNIV ANHUI SCIENCE & TECH | 2015-02-18 | — | — | CN | disclosed |
| WO-2014177876-A1 | CALCIUM SUPPLEMENT | CALINNOVA LTD (GB) | 2014-11-06 | — | — | WO | disclosed |
| US-20120121754-A1 | Dietary Supplement | CALLINOVA LTD (GB) | 2012-05-17 | — | — | US | disclosed |
| EP-2408317-A1 | DIETARY SUPPLEMENT | Calinnova Ltd (GB) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106351-A1 | DIETARY SUPPLEMENT | VETAFARM EUROPE LTD (GB) | 2010-09-23 | — | — | WO | disclosed |