SCHEMBL25312624

SCHEMBL25312624

C=CC(=O)Nc1ccc(NC2CCCCC2)c(-c2ccccn2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 6/20 0.53
▸ MAPK3 P27361 1/20 0.45
▸ MERTK Q12866 2/20 0.44
▸ AXL P30530 1/20 0.44
▸ FLT3 P36888 1/20 0.44
▸ TYRO3 Q06418 1/20 0.44
▸ GAS6 Q14393 1/20 0.44
▸ GPR39 O43194 2/20 0.42
▸ GRM4 Q14833 1/20 0.41
▸ ERBB2 P04626 1/20 0.41
▸ MET P08581 1/20 0.41
▸ KDR P35968 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31097790 1.00 EGFR (0.53) EGFRMAPK3MERTKAXLFLT3
SCHEMBL25311865 0.99 EGFR (0.51) EGFRMAPK3MERTKAXLFLT3
SCHEMBL31097830 0.99 EGFR (0.51) EGFRMAPK3MERTKAXLFLT3
SCHEMBL31097817 0.87 TYRO3 (0.41) EGFRMAPK3MERTKAXLFLT3
SCHEMBL25316844 0.87 TYRO3 (0.41) EGFRMAPK3MERTKAXLFLT3
SCHEMBL25314530 0.84 EGFR (0.52) EGFRMAPK3ALDH1A1MAPTKMT2A
SCHEMBL31097853 0.81 EGFR (0.50) EGFRMAPK3KDRKDM4E
SCHEMBL25311938 0.81 EGFR (0.50) EGFRMAPK3KDRKDM4E
SCHEMBL25876838 0.81 TGM2 (0.43) EGFR
SCHEMBL25312918 0.77 CCNK (0.47) EGFRCCNKCDK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-03-06 — — US claimed
EP-4464693-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT Daewoong Pharmaceutical Co., Ltd. (KR) 2024-11-20 — — EP claimed
WO-2023136645-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT 주식회사 대웅제약 2023-07-20 — — WO claimed
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-03-06 — — US disclosed
EP-4464693-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT Daewoong Pharmaceutical Co., Ltd. (KR) 2024-11-20 — — EP disclosed
WO-2023136645-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT 주식회사 대웅제약 2023-07-20 — — WO disclosed
WO-2023136645-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT 주식회사 대웅제약 2023-07-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient MKI67, CCNB1, ALDH7A1 EGFR 69/4885MAPK3 441/4885MERTK 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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