Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809558 | 0.89 | MAPT (0.67) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL25318094 | 0.85 | MAPT (0.72) | MAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL25315369 | 0.83 | MAPT (0.64) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL29524516 | 0.83 | MAPT (0.64) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL23581164 | 0.81 | MAPK1 (0.57) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL1844193 | 0.81 | MAPT (0.74) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL28505774 | 0.81 | MAPT (0.54) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL940811 | 0.80 | MAPT (0.78) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL22778043 | 0.80 | MAPT (0.79) | MAPTALDH1A1MAPK1PKMKMT2A | |
| SCHEMBL18036523 | 0.79 | MAPT (0.75) | MAPTALDH1A1MAPK1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217355-A1 | AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 | Forkhead Biotherapeutics, inc. (US) | 2023-08-02 | — | — | EP | disclosed |