SCHEMBL25314834

SCHEMBL25314834

Cc1c(C(=O)NN2CCS(=O)(=O)CC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(C#CCCO)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.63
CNR2 P34972 12/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25314723 0.93 CNR1 (0.54) CNR1CNR2
SCHEMBL24231239 0.92 CNR1 (0.63) CNR1CNR2
SCHEMBL25314685 0.92 CNR1 (0.61) CNR1CNR2
SCHEMBL2627899 0.91 CNR1 (0.76) CNR1CNR2
SCHEMBL31528998 0.91 CNR1 (0.76) CNR1CNR2
SCHEMBL25312789 0.91 CNR1 (0.60) CNR1CNR2
SCHEMBL31528994 0.90 CNR1 (0.77) CNR1CNR2
SCHEMBL25312062 0.90 CNR1 (0.55) CNR1CNR2
SCHEMBL25314506 0.90 CNR1 (0.58) CNR1CNR2
SCHEMBL25314389 0.90 CNR1 (0.58) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234928-A1 Novel Compounds for Treating Fibrosis and Inflammatory Conditions MAKSCIENTIFIC, LLC 2023-07-27 US claimed
US-20230234928-A1 Novel Compounds for Treating Fibrosis and Inflammatory Conditions MAKSCIENTIFIC, LLC 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234928-A1 Novel Compounds for Treating Fibrosis and Inflammatory Conditions CNR2, CNR1, GPR174 CNR1 2/4885CNR2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.