Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310191 | 1.00 | KDM2B (0.32) | KDM2BMAPTTSHR | |
| SCHEMBL22633315 | 1.00 | KDM2B (0.32) | KDM2BMAPTTSHR | |
| SCHEMBL599421 | 0.83 | MAPT (0.34) | KDM2BMAPTTSHR | |
| SCHEMBL599420 | 0.83 | MAPT (0.34) | KDM2BMAPTTSHR | |
| SCHEMBL599422 | 0.83 | MAPT (0.34) | KDM2BMAPTTSHR | |
| SCHEMBL15920668 | 0.82 | MAPT (0.36) | MAPTTSHR | |
| SCHEMBL3563797 | 0.81 | KDM2B (0.33) | KDM2B | |
| SCHEMBL22029860 | 0.77 | ATM (0.39) | — | |
| SCHEMBL21196005 | 0.77 | ATM (0.39) | — | |
| SCHEMBL6592886 | 0.77 | ATM (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |