Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599421 | 1.00 | MAPT (0.34) | MAPTKDM2BDPP4GAATSHR | |
| SCHEMBL599420 | 1.00 | MAPT (0.34) | MAPTKDM2BDPP4GAATSHR | |
| SCHEMBL22123150 | 0.85 | MAPT (0.34) | MAPTKDM2BDPP4GAATSHR | |
| SCHEMBL25310191 | 0.83 | KDM2B (0.32) | MAPTKDM2BTSHR | |
| SCHEMBL22633315 | 0.83 | KDM2B (0.32) | MAPTKDM2BTSHR | |
| SCHEMBL25315216 | 0.83 | KDM2B (0.32) | MAPTKDM2BTSHR | |
| SCHEMBL17714409 | 0.81 | MAPT (0.38) | MAPTGAATSHR | |
| SCHEMBL7879359 | 0.77 | MEN1 (0.39) | MAPTDPP4TSHR | |
| SCHEMBL7879740 | 0.77 | MEN1 (0.39) | MAPTDPP4TSHR | |
| SCHEMBL26676803 | 0.74 | LIPE (0.43) | MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040998-A1 | 2-ALKYL PIPERIDINE MGLUR5 RECEPTOR MODULATORS | MERCER SWATI P (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040998-A1 | 2-ALKYL PIPERIDINE MGLUR5 RECEPTOR MODULATORS | GRM5, GRIK5, GRM2 | MAPT 1329/4885KDM2B 2359/4885DPP4 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.