SCHEMBL25315941

SCHEMBL25315941

O=C1C[C@H]2CC[C@H](C1)N2C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1164960 1.00 MAPK1 (0.41) MAPK1MEN1KMT2APOLBGAA
SCHEMBL984359 1.00 MAPK1 (0.41) MAPK1MEN1KMT2APOLBGAA
SCHEMBL17101416 0.91 MAPK1 (0.54) MAPK1MEN1KMT2APOLBGAA
SCHEMBL935034 0.86 MEN1 (0.39) MAPK1MEN1KMT2A
SCHEMBL1573560 0.80 MAPK1 (0.33) MAPK1MEN1KMT2A
SCHEMBL30359026 0.80 MAPK1 (0.33) MAPK1MEN1KMT2A
SCHEMBL25244282 0.80 MAPK1 (0.33) MAPK1MEN1KMT2A
SCHEMBL17101422 0.79 MAPK1 (0.40) MAPK1MEN1KMT2A
SCHEMBL12357441 0.79 MAPK1 (0.45) MAPK1MEN1KMT2A
SCHEMBL17101420 0.79 MAPK1 (0.40) MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 WO disclosed