Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984359 | 0.86 | MAPK1 (0.41) | MEN1KMT2AMAPK1 | |
| SCHEMBL1164960 | 0.86 | MAPK1 (0.41) | MEN1KMT2AMAPK1 | |
| SCHEMBL25315941 | 0.86 | MAPK1 (0.41) | MEN1KMT2AMAPK1 | |
| SCHEMBL17101416 | 0.82 | MAPK1 (0.54) | MEN1KMT2AMAPK1 | |
| SCHEMBL1573560 | 0.80 | MAPK1 (0.33) | MEN1KMT2AMAPK1 | |
| SCHEMBL25244282 | 0.80 | MAPK1 (0.33) | MEN1KMT2AMAPK1 | |
| SCHEMBL15174472 | 0.71 | MAPK1 (0.32) | MEN1KMT2AMAPK1 | |
| SCHEMBL6205613 | 0.71 | MAPK1 (0.32) | MEN1KMT2AMAPK1 | |
| SCHEMBL21997842 | 0.71 | MAPK1 (0.32) | MEN1KMT2AMAPK1 | |
| SCHEMBL12545158 | 0.71 | MAPK1 (0.32) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008312-A2 | INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-01-20 | — | — | WO | disclosed |