Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30508719 | 1.00 | CSNK2A1 (0.42) | CSNK2A1L3MBTL1ADORA2AADORA2BADORA1 | |
| SCHEMBL30277586 | 0.85 | L3MBTL1 (0.34) | L3MBTL1ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL30508720 | 0.79 | L3MBTL1 (0.36) | L3MBTL1 | |
| SCHEMBL29187093 | 0.78 | L3MBTL1 (0.37) | CSNK2A1L3MBTL1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL29187092 | 0.78 | L3MBTL1 (0.37) | CSNK2A1L3MBTL1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL16662380 | 0.78 | ADORA2A (0.35) | CSNK2A1ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL31150519 | 0.77 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KDM4ENPC1HTT | |
| SCHEMBL25316860 | 0.77 | L3MBTL1 (0.33) | L3MBTL1ALDH1A1KDM4ENPC1HTT | |
| SCHEMBL13792503 | 0.76 | — | — | |
| SCHEMBL30508875 | 0.75 | L3MBTL1 (0.32) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |