Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949488 | 0.85 | AAK1 (0.61) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL29254128 | 0.85 | AAK1 (0.61) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL16671958 | 0.85 | AAK1 (0.61) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL25319741 | 0.85 | AAK1 (0.65) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL30949484 | 0.83 | AAK1 (0.65) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL3219664 | 0.83 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL548007 | 0.83 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL548006 | 0.83 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL5981707 | 0.83 | AAK1 (0.61) | AAK1PPARGPPARACNR1ITGA4 | |
| SCHEMBL5981702 | 0.83 | AAK1 (0.61) | AAK1PPARGPPARACNR1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |