Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981702 | 1.00 | AAK1 (0.61) | AAK1PPARGPPARACNR1CNR2 | |
| SCHEMBL548006 | 0.91 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL3219664 | 0.91 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL548007 | 0.91 | AAK1 (0.68) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL12568248 | 0.89 | AAK1 (0.62) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL29389786 | 0.89 | AAK1 (0.62) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL22033186 | 0.89 | AAK1 (0.62) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL30949483 | 0.89 | AAK1 (0.62) | AAK1PPARGPPARAITGA4ITGB7 | |
| SCHEMBL18511393 | 0.88 | AAK1 (0.65) | AAK1PPARGPPARACNR1ITGA4 | |
| SCHEMBL977220 | 0.88 | AAK1 (0.61) | AAK1PPARGPPARAITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115766-B2 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORP. (US) | 2006-10-03 | — | — | US | disclosed |
| US-20040034246-A1 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| WO-2002044144-A2 | NUCLEOPHILIC APPROACH FOR PREPARING RADIOLABELED IMAGING AGENTS AND ASSOCIATED COMPOUNDS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034246-A1 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | SNCA, PARK7, SAMHD1 | AAK1 3662/4885PPARG 3359/4885PPARA 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.