SCHEMBL25318358

SCHEMBL25318358

[O]Cc1ccc(Cl)c2cc(F)oc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25323515 0.83 CYP1A2 (0.31) AHR
SCHEMBL25402675 0.83 AHR (0.31) AHR
SCHEMBL30474198 0.83 CYP1A2 (0.31) AHR
SCHEMBL30538815 0.80
SCHEMBL30538809 0.80
SCHEMBL25406100 0.76 KDM4E (0.45)
SCHEMBL25404609 0.76 NOTUM (0.41)
SCHEMBL31347707 0.73 RARA (0.42) AHR
SCHEMBL25320227 0.73 RARA (0.42) AHR
SCHEMBL31038589 0.72 GRIN1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138684-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO , INC. (US) 2023-07-27 WO disclosed