⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342405 | 0.94 | — | — | |
| SCHEMBL31277248 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL2945963 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL14641322 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL2945960 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL16505672 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL15285099 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL30895203 | 0.92 | ALDH1A1 (0.30) | — | |
| SCHEMBL4021119 | 0.78 | — | — | |
| SCHEMBL4027953 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6228094-A | — | — | None | — | — | JP | disclosed |
| CN-120004902-A | Heteroaryl heterocycles and uses thereof | 和记黄埔医药（上海）有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119925375-A | Heteroaryl heterocycles and uses thereof | 和记黄埔医药（上海）有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930630-A | Heteroaryl heterocycles and uses thereof | 和记黄埔医药（上海）有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115151535-B | Heteroaryl heterocycles and uses thereof | 和记黄埔医药（上海）有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2024109688-A1 | PYRROLE FUSED RING DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 成都百裕制药股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-114478424-B | Preparation method of azlactone derivative with cycloalkenyl substituted at beta position | 浙江工业大学 | 2023-09-26 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11478474-B2 | 2-(3′-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4′-bipyridin]-2′-yl)-7,7-dimethyl-7,8-dihydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one as a BTK inhibitor | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-10-25 | — | — | US | disclosed |
| CN-115151535-A | Heteroaryl heterocyclic compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | AJINOMOTO CO. INC (JP) | 2009-07-02 | — | — | US | disclosed |
| US-7517996-B2 | Azole compound | AJINOMOTO CO., INC. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20060194850-A1 | Novel azole compound | AJINOMOTO CO. INC (JP) | 2006-08-31 | — | — | US | disclosed |
| WO-2005049568-A1 | A PROCESS FOR INDUSTRIALLY VIABLE PREPARATION OF (S,S,S) PHENYLMETHYL-2-AZABICYCLO-[3.3.0]-OCTANE-3-CARBOXYLATE TOSYLATE | BABU POTLURI RAMESH (IN) | 2005-06-02 | — | — | WO | disclosed |
| US-5550255-A | Cis, endo-2-azabicycloalkane-3-carboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-27 | — | — | US | disclosed |
| JP-H06228094-A | CIS, ENDO-2-AZABICYCLOALKANE-3-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | HOECHST AG | 1994-08-16 | — | — | JP | disclosed |
| EP-0173199-B1 | Cis, endo-2-azabicycloalkane-3-carboxylic-acid derivatives, processes for their manufacture, their use and intermediate products obtained in their manufacture | HOECHST AG (DE) | 1994-07-13 | — | — | EP | disclosed |
| US-4886827-A | Cis,endo-2-azabicycloalkane-3-carboxylic acid derivatives, their use and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0174071-A2 | Dihydropyridine derivatives and their production, formulation and use as pharmaceuticals | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
| EP-0173199-A1 | Cis, endo-2-azabicycloalkane-3-carboxylic-acid derivatives, processes for their manufacture, their use and intermediate products obtained in their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-05 | — | — | EP | disclosed |