⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854358 | 0.80 | — | — | |
| SCHEMBL966653 | 0.69 | — | — | |
| SCHEMBL25242685 | 0.67 | — | — | |
| SCHEMBL17603062 | 0.66 | — | — | |
| Bicarbonate SCHEMBL5539995 | 0.66 | TSHR (0.39) | — | |
| SCHEMBL2443389 | 0.66 | — | — | |
| SCHEMBL5688650 | 0.65 | — | — | |
| SCHEMBL22436234 | 0.65 | — | — | |
| SCHEMBL12837724 | 0.65 | TSHR (0.40) | — | |
| SCHEMBL11571635 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412961-A | Pesticidally active heteroaromatic compounds | 先正达农作物保护股份公司 | 2024-01-16 | — | — | CN | disclosed |
| US-20230364070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | ANTARES THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| EP-4217070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066734-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |