⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31083339 | 0.97 | — | — | |
| Butynamine SCHEMBL2109905 | 0.73 | — | — | |
| SCHEMBL14372109 | 0.66 | — | — | |
| SCHEMBL25319601 | 0.66 | — | — | |
| SCHEMBL11854358 | 0.66 | — | — | |
| SCHEMBL2277776 | 0.65 | — | — | |
| SCHEMBL299989 | 0.64 | — | — | |
| SCHEMBL1726984 | 0.64 | — | — | |
| SCHEMBL29854 | 0.62 | — | — | |
| SCHEMBL16804666 | 0.62 | LMNA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107321-A1 | HETEROCYCLIC COMPOUNDS USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2026041636-A1 | MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2026-02-26 | — | — | WO | disclosed |
| CN-119823103-A | Polycyclic derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-15 | — | — | CN | disclosed |
| WO-2024245193-A1 | HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-12-05 | — | — | WO | disclosed |
| US-20240307406-A1 | Device for determining the attitude of a carrier, and associated system for assisting with the piloting of a carrier and determination method | ADVANCED BIODESIGN (FR) | 2024-09-19 | — | — | US | disclosed |
| CN-117320706-A | Aminothiol ester compounds or derivatives thereof as immunomodulators | 高级生物设计公司 | 2023-12-29 | — | — | CN | disclosed |
| EP-4284360-A1 | AMINOTHIOLESTER COMPOUND OR DERIVATIVE THEREOF FOR USE AS AN IMMUNOMODULATORY AGENT | Advanced Biodesign (FR) | 2023-12-06 | — | — | EP | disclosed |
| US-20220363666-A1 | TYROSINE KINASE INHIBITOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | US | disclosed |
| US-20220265845-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | ADVANCED BIODESIGN (FR) | 2022-08-25 | — | — | US | disclosed |
| WO-2022162196-A1 | AMINOTHIOLESTER COMPOUND OR DERIVATIVE THEREOF FOR USE AS AN IMMUNOMODULATORY AGENT | ADVANCED BIODESIGN (FR) | 2022-08-04 | — | — | WO | disclosed |
| WO-2008107321-A1 | HETEROCYCLIC COMPOUNDS USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |
| US-20070032476-A1 | Aminothiolester compounds, pharmaceutical and cosmetic compositions containing same and uses thereof | CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-02-08 | — | — | US | disclosed |
| US-7078402-B2 | Aminothiol ester compounds, pharmaceutical and cosmetics compositions containing same and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-07-18 | — | — | US | disclosed |
| EP-1296946-B1 | AMINOTHIOLESTER COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES THEREOF | GALDERMA RES & DEV (FR) | 2004-04-21 | — | — | EP | disclosed |
| US-20030181443-A1 | Aminothiolester compounds, pharmaceutical and cosmetic compositions containing same and uses thereof | ADVANCED BIODESIGN (FR) | 2003-09-25 | — | — | US | disclosed |
| EP-1296946-A1 | AMINOTHIOLESTER COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES THEREOF | Galderma Research & Development, S.N.C. (FR) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001092220-A1 | AMINOTHIOLESTER COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES THEREOF | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-12-06 | — | — | WO | disclosed |
| US-5789448-A | TYROSINE KINASE INHIBITORS; ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0721930-A1 | BENZOYLETHYLENE DERIVATIVE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-3969415-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |