Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319825 | 0.95 | NLRP3 (0.86) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25318867 | 0.95 | NLRP3 (0.86) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25319719 | 0.95 | NLRP3 (0.86) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25319045 | 0.94 | NLRP3 (1.00) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25317965 | 0.94 | NLRP3 (0.85) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25902003 | 0.94 | NLRP3 (1.00) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25320335 | 0.94 | NLRP3 (1.00) | NLRP3TP53MAPT | |
| SCHEMBL25316885 | 0.92 | NLRP3 (0.82) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25902008 | 0.92 | NLRP3 (1.00) | NLRP3SMN1; SMN2TP53MAPT | |
| SCHEMBL25318856 | 0.92 | NLRP3 (0.89) | NLRP3SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137885-A1 | COMPOUND HAVING PYRIDOIMIDAZOLE AS PARENT NUCLEUS, AND PREPARATION METHOD FOR AND USE OF COMPOUND | 中国药科大学 | 2023-07-27 | — | — | WO | disclosed |
| CN-114349758-A | Compound with pyridine imidazole as parent nucleus and preparation method and application thereof | 中国药科大学 | 2022-04-15 | — | — | CN | disclosed |