Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551319 | 1.00 | PRMT5 (0.39) | PRMT5WDR77KCNH2 | |
| SCHEMBL25320136 | 0.95 | PRMT5 (0.39) | PRMT5WDR77KCNH2 | |
| SCHEMBL25320139 | 0.95 | PRMT5 (0.39) | PRMT5WDR77KCNH2 | |
| SCHEMBL25320830 | 0.93 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL25320828 | 0.93 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL30551565 | 0.91 | PRMT5 (0.36) | PRMT5WDR77KCNH2 | |
| SCHEMBL25321214 | 0.91 | PRMT5 (0.36) | PRMT5WDR77KCNH2 | |
| SCHEMBL25320591 | 0.85 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL25323120 | 0.84 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL30551462 | 0.84 | PRMT5 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |