Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069563 | 0.75 | DDB1 (0.39) | TNKSPARP1TNKS2HPGDDDB1 | |
| SCHEMBL710428 | 0.69 | ALDH1A1 (0.67) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL708661 | 0.69 | ALDH1A1 (0.62) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL710523 | 0.69 | ALDH1A1 (0.62) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6125325 | 0.69 | ALDH1A1 (0.62) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL710509 | 0.69 | ALDH1A1 (0.56) | PARP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL31121628 | 0.68 | PDE6A (0.31) | — | |
| SCHEMBL6069811 | 0.68 | PARP1 (0.35) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL25117686 | 0.68 | PDE6A (0.31) | — | |
| SCHEMBL6137586 | 0.66 | PARP1 (0.34) | TNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134647-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 优领医药科技(香港)有限公司 | 2023-07-20 | — | — | WO | disclosed |