Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321690 | 0.85 | MKNK1 (0.34) | MKNK1MKNK2 | |
| SCHEMBL25319641 | 0.83 | CA12 (0.39) | — | |
| SCHEMBL25317322 | 0.72 | BCHE (0.46) | MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL25319420 | 0.72 | ATAD2 (0.38) | MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL31555351 | 0.68 | CYP17A1 (0.38) | MKNK1MKNK2 | |
| SCHEMBL25318788 | 0.68 | CYP17A1 (0.38) | MKNK1MKNK2 | |
| SCHEMBL11058044 | 0.66 | KMT2A (0.41) | ALDH1A1 | |
| SCHEMBL23745465 | 0.66 | MKNK2 (0.38) | MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL23727834 | 0.66 | MKNK2 (0.38) | MKNK1MKNK2KDM4EALDH1A1 | |
| Fluoride SCHEMBL11791995 | 0.65 | ABCC1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139379-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE (ROCK) | REDX PHARMA PLC (GB) | 2023-07-27 | — | — | WO | disclosed |