⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283111 | 0.97 | — | — | |
| SCHEMBL16894426 | 0.97 | — | — | |
| SCHEMBL4640661 | 0.97 | — | — | |
| SCHEMBL980219 | 0.90 | — | — | |
| SCHEMBL9984 | 0.82 | — | — | |
| SCHEMBL8984071 | 0.82 | ALOX15 (0.30) | — | |
| SCHEMBL4652997 | 0.78 | ALOX15 (0.33) | — | |
| SCHEMBL30140053 | 0.78 | ALOX15 (0.33) | — | |
| SCHEMBL22821839 | 0.78 | ALOX15 (0.33) | — | |
| SCHEMBL2636314 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034084-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARM INC (US) | 2026-02-05 | — | — | US | disclosed |
| US-12427130-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2025-09-30 | — | — | US | disclosed |
| US-12378263-B2 | Modulators of sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| EP-3615019-B1 | MODULATOR OF SESTRIN-GATOR2 INTERACTION FOR USE IN THE TREATMENT OF TREATMENT-RESISTANT DEPRESSION | NAVITOR PHARM INC (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-4556069-A2 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-118439921-A | Preparation method of trans-1-bromo-4- [4- (trifluoroalkyl) cyclohexyl ] benzene compound | 陕西莱特光电材料股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-20240091184-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2024-03-21 | — | — | US | disclosed |
| CN-116370448-A | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-07-04 | — | — | CN | disclosed |
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-7968584-B2 | Substituted arylpyrazoles | PFIZER INC. (US) | 2011-06-28 | — | — | US | disclosed |
| WO-2010119878-A1 | PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
| EP-1893581-B1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | PFIZER LTD (GB) | 2010-01-27 | — | — | EP | disclosed |
| US-20090186924-A1 | SUBSTITUTED ARYLPYRAZOLES | PFIZER INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7538134-B2 | Substituted arylpyrazoles | PFIZER INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1951382-A1 | FIRE EXTINGUISHING AND FIRE SUPPRESSION COMPOSITIONS COMPRISING UNSATURATE FLOUOROCARBONS | GREAT LAKES CHEMICAL CORPORATION (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1893581-A1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | Pfizer Limited (GB) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007059468-A1 | FIRE EXTINGUISHING AND FIRE SUPPRESSION COMPOSITIONS COMPRISING UNSATURATE FLOUOROCARBONS | GREAT LAKES CHEMICAL CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20060287365-A1 | Substituted arylpyrazoles | ZOETIS LLC | 2006-12-21 | — | — | US | disclosed |
| WO-2006134468-A1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | PFIZER LIMITED (GB) | 2006-12-21 | — | — | WO | disclosed |