Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9895421 | 1.00 | POLB (0.41) | POLBL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL17892791 | 1.00 | POLB (0.41) | POLBL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL9898712 | 0.85 | THRB (0.33) | ALDH1A1LMNA | |
| SCHEMBL9918107 | 0.85 | POLB (0.41) | POLBL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL9900151 | 0.83 | KDM4E (0.33) | ALDH1A1LMNAMAPTLIPE | |
| SCHEMBL21521134 | 0.82 | POLB (0.34) | POLBL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL13505392 | 0.82 | POLB (0.34) | POLBL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL1913994 | 0.82 | POLB (0.34) | POLBL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL17686396 | 0.81 | — | — | |
| SCHEMBL17803667 | 0.78 | POLB (0.42) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |