Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322702 | 1.00 | NOTUM (0.33) | NOTUMSYKSLC5A2MLLT1 | |
| SCHEMBL25320574 | 0.90 | SLC5A2 (0.37) | SLC5A2MLLT1 | |
| SCHEMBL25320575 | 0.90 | SLC5A2 (0.37) | SLC5A2MLLT1 | |
| SCHEMBL25321615 | 0.88 | SLC5A2 (0.36) | SLC5A2MLLT1 | |
| SCHEMBL25323488 | 0.85 | IRAK4 (0.33) | — | |
| SCHEMBL24366024 | 0.84 | MAPT (0.43) | SYK | |
| SCHEMBL25916910 | 0.84 | MAPT (0.43) | SYK | |
| SCHEMBL25321611 | 0.81 | TLR8 (0.34) | — | |
| SCHEMBL25321613 | 0.81 | TLR8 (0.34) | — | |
| SCHEMBL25324200 | 0.81 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | RB1, CYP1B1, REN | NOTUM 3380/4885SYK 1992/4885SLC5A2 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.