Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918193 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL17066472 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL25918192 | 0.82 | CHRNB4 (0.46) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL25319906 | 0.82 | CHRNB4 (0.46) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL17987646 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL26984257 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL25319908 | 0.82 | CHRNB4 (0.46) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL24233804 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL22473177 | 0.82 | MEN1 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL20690005 | 0.72 | CHRNB2 (0.43) | MEN1KMT2ACHRNB2CHRNA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |