Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320775 | 0.91 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25320029 | 0.91 | PDE2A (0.33) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25324020 | 0.89 | PDE2A (0.33) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25324023 | 0.87 | PDE2A (0.32) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25320978 | 0.77 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25899012 | 0.72 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL30886293 | 0.70 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25899217 | 0.69 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25322283 | 0.69 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31178973 | 0.68 | AXL (0.43) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |