Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320029 | 0.98 | PDE2A (0.33) | PDE2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL25324023 | 0.95 | PDE2A (0.32) | PDE2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL25322907 | 0.89 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25320775 | 0.76 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL15081232 | 0.74 | ALDH1A1 (0.35) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL25917748 | 0.74 | PDE2A (0.41) | PDE2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31156165 | 0.73 | SCN9A (0.37) | PDE2AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22717640 | 0.73 | SCN9A (0.37) | PDE2AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21979362 | 0.71 | HTT (0.36) | PDE2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30901316 | 0.71 | HTT (0.36) | PDE2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |