Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.48 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550691 | 1.00 | TIPARP (0.48) | TIPARPFLT3HTR1AHTR2ADRD2 | |
| SCHEMBL25323234 | 1.00 | TIPARP (0.48) | TIPARPFLT3HTR1AHTR2ADRD2 | |
| SCHEMBL25320875 | 0.87 | TIPARP (0.54) | TIPARPHTR1AHTR2ADRD2 | |
| SCHEMBL30550884 | 0.87 | TIPARP (0.54) | TIPARPHTR1AHTR2ADRD2 | |
| SCHEMBL25320871 | 0.87 | TIPARP (0.54) | TIPARPHTR1AHTR2ADRD2 | |
| SCHEMBL30550829 | 0.86 | TIPARP (0.49) | TIPARPFLT3HTR1AHTR2ADRD2 | |
| SCHEMBL25322618 | 0.86 | TIPARP (0.49) | TIPARPFLT3HTR1AHTR2ADRD2 | |
| SCHEMBL25322613 | 0.86 | TIPARP (0.49) | TIPARPFLT3HTR1AHTR2ADRD2 | |
| SCHEMBL25324753 | 0.83 | TIPARP (0.51) | TIPARP | |
| SCHEMBL25324750 | 0.83 | TIPARP (0.51) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459922-B2 | PARP7 inhibitors | GILEAD SCIENCES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-20230365529-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459922-B2 | PARP7 inhibitors | PARP1, PARP11, PARP2 | TIPARP 491/4885FLT3 2225/4885HTR1A 1056/4885 |
| US-20230365529-A1 | PARP7 INHIBITORS | PARP1, PARP11, PARP2 | TIPARP 491/4885FLT3 2225/4885HTR1A 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.