Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30470833 | 0.89 | NPC1 (0.44) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL31145099 | 0.89 | NPC1 (0.44) | PPARADYRK1AADORA1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL23850548 | 0.74 | P2RY14 (0.45) | LMNAHDAC4P2RY14 | |
| SCHEMBL30470569 | 0.72 | DYRK1A (0.39) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL29081519 | 0.72 | PPARA (0.40) | PPARADYRK1AADORA1LMNATP53 | |
| Formaldehyde SCHEMBL25322525 | 0.72 | DYRK1A (0.39) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL25922452 | 0.71 | NPC1 (0.42) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL30470911 | 0.71 | NPC1 (0.42) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL25335395 | 0.71 | RAB9A (0.46) | PPARADYRK1AADORA1NPC1RAB9A | |
| SCHEMBL16132861 | 0.70 | NPC1 (0.52) | PPARADYRK1AADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |