Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326442 | 0.79 | SIGMAR1 (0.35) | GRIA2SIGMAR1CSNK1DTHRBTGFBR1 | |
| SCHEMBL25321487 | 0.78 | NPC1 (0.41) | ALDH1A1SLC34A1CSNK1DTGFBR1MAPK14 | |
| SCHEMBL25324809 | 0.77 | CSNK1D (0.39) | SLC34A1CSNK1DTHRBTGFBR1MAPK14 | |
| SCHEMBL25323896 | 0.76 | CSNK1D (0.35) | CSNK1DTGFBR1MAPK14 | |
| SCHEMBL25323924 | 0.74 | S1PR1 (0.36) | HCRTR1HCRTR2CSNK1DTGFBR1MAPK14 | |
| SCHEMBL30509533 | 0.72 | SIGMAR1 (0.41) | SIGMAR1NTRK1CSNK1DTGFBR1MAPK14 | |
| SCHEMBL26661574 | 0.72 | SIGMAR1 (0.41) | SIGMAR1NTRK1CSNK1DTGFBR1MAPK14 | |
| SCHEMBL25321143 | 0.72 | CSNK1D (0.41) | ALDH1A2ALDH1A1ALDH1A3SLC34A1CSNK1D | |
| SCHEMBL30509325 | 0.72 | CSNK1D (0.41) | ALDH1A2ALDH1A1ALDH1A3SLC34A1CSNK1D | |
| SCHEMBL25324060 | 0.71 | MAPK14 (0.36) | SIGMAR1CSNK1DTHRBTGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | ALDH1A2 2412/4885ALDH1A1 1600/4885ALDH1A3 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.