Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL25323728 | 1.00 | PRMT5 (0.57) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL25324578 | 0.99 | PRMT5 (0.58) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL25324576 | 0.99 | PRMT5 (0.58) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL24367528 | 0.87 | PRMT5 (0.57) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL29477756 | 0.83 | PRMT5 (0.54) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL24366978 | 0.82 | PRMT5 (0.56) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL24366650 | 0.82 | PRMT5 (0.56) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL5516152 | 0.78 | PRMT5 (0.52) | PRMT5WDR77ALDH1A1GLAHPGD | |
| SCHEMBL25321486 | 0.78 | RIPK1 (0.43) | PRMT5WDR77ALDH1A1RIPK1CHRNB2 | |
| SCHEMBL25321489 | 0.78 | RIPK1 (0.43) | PRMT5WDR77ALDH1A1RIPK1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |