Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551470 | 1.00 | PRMT5 (0.45) | PRMT5WDR77RIPK1FABP7TACR1 | |
| SCHEMBL25918195 | 0.96 | PRMT5 (0.48) | PRMT5WDR77RIPK1FABP7TACR1 | |
| SCHEMBL25321623 | 0.96 | PRMT5 (0.48) | PRMT5WDR77RIPK1FABP7TACR1 | |
| SCHEMBL25321619 | 0.96 | PRMT5 (0.48) | PRMT5WDR77RIPK1FABP7TACR1 | |
| SCHEMBL25325873 | 0.80 | PDK1 (0.37) | RIPK1FABP7TACR1 | |
| SCHEMBL24366565 | 0.79 | PRMT5 (0.47) | PRMT5WDR77RIPK1FABP7TACR1 | |
| SCHEMBL25327021 | 0.77 | PDK1 (0.39) | RIPK1FABP7TACR1 | |
| SCHEMBL30522878 | 0.77 | NR1H2 (0.39) | RIPK1TACR1 | |
| SCHEMBL30551093 | 0.77 | KDM4E (0.40) | PRMT5WDR77L3MBTL1 | |
| SCHEMBL25325871 | 0.76 | PDK1 (0.37) | RIPK1FABP7TACR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |