Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866965 | 0.86 | PTGDR2 (0.43) | PTGDR2SRCSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29959159 | 0.85 | PTGDR2 (0.48) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL1154907 | 0.85 | PTGDR2 (0.48) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL30751165 | 0.84 | ENPP3 (0.44) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL5661951 | 0.84 | ENPP3 (0.44) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL20765258 | 0.82 | ENPP3 (0.43) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL23910826 | 0.82 | ENPP3 (0.48) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 | |
| SCHEMBL5564252 | 0.81 | SRC (0.41) | PTGDR2SRCSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30440833 | 0.81 | SRC (0.41) | PTGDR2SRCSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL22285821 | 0.81 | PTGDR2 (0.42) | ENPP3ENPP1PTGDR2SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339900-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK2A1 | ENPP3 4254/4885ENPP1 3790/4885PTGDR2 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.