Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 11/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326285 | 0.93 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL25327039 | 0.93 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL30522917 | 0.90 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL25325002 | 0.86 | NTRK1 (0.34) | PRMT5WDR77 | |
| SCHEMBL30522949 | 0.86 | NTRK1 (0.34) | PRMT5WDR77 | |
| SCHEMBL25325008 | 0.86 | NTRK1 (0.34) | PRMT5WDR77 | |
| SCHEMBL25326540 | 0.83 | PIK3CA (0.31) | — | |
| SCHEMBL30522975 | 0.81 | NTRK1 (0.31) | — | |
| SCHEMBL25324421 | 0.79 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL30522982 | 0.79 | PRMT5 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |