SCHEMBL2532769

SCHEMBL2532769

O=C(C(=O)C1NCCS1)C1NCCS1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28168212 0.84
SCHEMBL23421623 0.84 MAPT (0.32) MAPTCYP1A2
SCHEMBL8357 0.82
SCHEMBL23170 0.82
SCHEMBL2030154 0.82
SCHEMBL29039860 0.82 MAPT (0.31) MAPT
SCHEMBL29039861 0.82 MAPT (0.31) MAPT
SCHEMBL643272 0.80
SCHEMBL1810025 0.80
SCHEMBL6592973 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112220768-A Preparation method of miglitol tablets 四川维奥制药有限公司 2021-01-15 CN disclosed
EP-1801087-B1 CIS-1,2-SUBSTITUTED STILBENE DERIVATIVES FOR TREATING AND/OR PREVENTING DIABETES INST RADIATION MED AMMS PLA (CN) 2012-08-29 EP disclosed
US-8039513-B2 Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) 2011-10-18 US disclosed
US-20090161561-A1 Method and system for determining characters of channels HUAWEI TECHNOLOGIES CO., LTD 2009-06-25 US disclosed
US-20090076114-A1 Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) 2009-03-19 US disclosed
EP-1801087-A1 CIS-1,2-SUBSTITUTED STILBENE DERIVATES AND THE USE THEREROF FOR MANUFACTURING MEDICAMENTS FOR TREATING MEDICAMENTS FOR TREATING AND/OR PREVENTING DIABETES Institute of Radiation Medicine, Academy of Military Medical Sciences Pla (CN) 2007-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076114-A1 Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes SLC5A1, SLC5A2, SLC2A1 MAPT 2930/4885CYP1A2 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.