Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677099 | 0.77 | HTT (0.45) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL18133120 | 0.74 | CYP1B1 (0.46) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL518484 | 0.74 | HTT (0.52) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL15710896 | 0.73 | MAPT (0.49) | HTTSMN1; SMN2MAPTTHRBLMNA | |
| SCHEMBL6132425 | 0.73 | CYP1B1 (0.49) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL6132428 | 0.73 | CYP1B1 (0.49) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL15939608 | 0.72 | ALDH1A1 (0.49) | HTTSMN1; SMN2MAPTTHRBIDO1 | |
| SCHEMBL24130390 | 0.72 | MAPT (0.59) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL12670654 | 0.72 | MAPT (0.64) | CYP1B1HTTSMN1; SMN2MAPTTHRB | |
| SCHEMBL11730442 | 0.72 | MAPT (0.64) | CYP1B1HTTSMN1; SMN2MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696037-A | Azacyclic amide derivatives, preparation method and medical application thereof | 翰森生物有限责任公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023143355-A1 | AZACYCLE AMIDE DERIVATIVE, PREPARATION METHODS AND MEDICINAL USES THEREOF | HANSOH BIO LLC (US) | 2023-08-03 | — | — | WO | disclosed |