Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.61 |
| ▸ | CDK7 | P50613 | 1/20 | 0.61 |
| ▸ | PTK2 | Q05397 | 11/20 | 0.60 |
| ▸ | INSR | P06213 | 3/20 | 0.54 |
| ▸ | IGF1R | P08069 | 3/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.54 |
| ▸ | CCNK | O75909 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CCND3 | P30281 | 1/20 | 0.54 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.54 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328494 | 1.00 | CDK9 (0.61) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL31006849 | 0.93 | CDK9 (0.53) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25330054 | 0.90 | CDK9 (0.54) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25330047 | 0.90 | CDK9 (0.54) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25328196 | 0.90 | PTK2 (0.55) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25328192 | 0.90 | PTK2 (0.55) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25328850 | 0.90 | PTK2 (0.55) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL25328855 | 0.90 | PTK2 (0.55) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL13832520 | 0.87 | CDK7 (0.65) | CDK9CDK7PTK2INSRIGF1R | |
| SCHEMBL15600963 | 0.87 | CDK7 (0.65) | CDK9CDK7PTK2INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |