Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514687 | 0.85 | KDM1A (0.35) | — | |
| SCHEMBL30232420 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 | |
| SCHEMBL17514785 | 0.81 | ABCB1 (0.37) | DPP4MAPT | |
| SCHEMBL17918746 | 0.80 | HTR2C (0.46) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL25330066 | 0.80 | USP7 (0.46) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 | |
| SCHEMBL31222976 | 0.76 | KDM1A (0.50) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL19069574 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL17916114 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL1765128 | 0.75 | HTR1A (0.67) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 | |
| Hydrochloric Acid SCHEMBL6075201 | 0.73 | HTR1A (0.65) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |