Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917486 | 0.87 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| Hydrochloric Acid SCHEMBL22396515 | 0.85 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL839098 | 0.85 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2KDM1A | |
| SCHEMBL30955759 | 0.81 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL599855 | 0.81 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL599980 | 0.81 | SMYD2 (0.48) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL2017541 | 0.81 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL30955729 | 0.81 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL30726327 | 0.81 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2IDO1 | |
| SCHEMBL30927561 | 0.80 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |