Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31131379 | 1.00 | AR (0.41) | ARTRPV4CYP11B1CYP11B2PGR | |
| SCHEMBL3335216 | 0.82 | AR (0.41) | ARTRPV4CYP11B1CYP11B2PGR | |
| SCHEMBL31131413 | 0.77 | AR (0.45) | ARTRPV4CYP11B1CYP11B2PGR | |
| SCHEMBL25330095 | 0.77 | AR (0.45) | ARTRPV4CYP11B1CYP11B2PGR | |
| SCHEMBL221885 | 0.74 | AR (0.58) | ARPGR | |
| SCHEMBL15421833 | 0.74 | AR (0.42) | ARTRPV4CYP11B1CYP11B2PGR | |
| SCHEMBL31131407 | 0.74 | AR (0.43) | ARPGR | |
| SCHEMBL25329498 | 0.74 | AR (0.43) | ARPGR | |
| SCHEMBL16960193 | 0.71 | AR (0.37) | AR | |
| SCHEMBL29378798 | 0.69 | AR (0.41) | ARTRPV4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |