SCHEMBL25330837

SCHEMBL25330837

CSCCCCCC(=O)CCN=C=S

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 6/20 0.62
MIF P14174 3/20 0.36
NAAA Q02083 1/20 0.36
GSK3B P49841 1/20 0.35
KEAP1 Q14145 3/20 0.35
NFE2L2 Q16236 3/20 0.35
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
BACH1 O14867 1/20 0.33
MAFK O60675 1/20 0.33
EGFR P00533 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
RNPEP Q9H4A4 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25333089 0.93 TRPA1 (0.60) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL3115548 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL3123984 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL2679812 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL5352877 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL25332310 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL1020887 0.78 TRPA1 (1.00) TRPA1MIFNAAAGSK3BKEAP1
Erucin SCHEMBL435774 0.76
SCHEMBL25332536 0.74 MIF (0.34) TRPA1MIFNAAAGSK3BKEAP1
SCHEMBL668271 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066293-A1 OIL-BASED ISOTHIOCYANATE PRODUCTS AND PROCESSES FOR PREPARING OIL-BASED ISOTHIOCYANATE PRODUCTS BRASSICA PROTECTION PRODUCTS LLC (US) 2025-02-27 US disclosed
WO-2023133494-A2 OIL-BASED ISOTHIOCYANATE PRODUCTS AND PROCESSES FOR PREPARING OIL-BASED ISOTHIOCYANATE PRODUCTS BRASSICA PROTECTION PRODUCTS LLC (US) 2023-07-13 WO disclosed