Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880501 | 0.83 | PRKCI (0.62) | PRKCISORT1SMARCA2SMARCA4SMN1; SMN2 | |
| SCHEMBL30530884 | 0.80 | SREBF2 (0.45) | NOS3NOS1NOS2PRKCI | |
| SCHEMBL28292631 | 0.80 | PRKCI (0.48) | PRKCISORT1SMARCA2SMARCA4SMN1; SMN2 | |
| SCHEMBL19306076 | 0.78 | PRKCI (0.46) | PRKCISORT1SMARCA2SMARCA4SMN1; SMN2 | |
| SCHEMBL28940889 | 0.77 | PRKCI (0.46) | PRKCISORT1SMARCA2SMARCA4KMT2A | |
| SCHEMBL15880685 | 0.74 | SMARCA2 (0.65) | SORT1SMARCA2SMARCA4KMT2A | |
| SCHEMBL1336857 | 0.74 | CCNC (0.48) | PRKCISMARCA2SMARCA4SMN1; SMN2NPC1 | |
| SCHEMBL23015823 | 0.72 | PRKCI (0.61) | PRKCINPC1RAB9ALMNAKMT2A | |
| SCHEMBL25174663 | 0.72 | ANO1 (0.44) | PRKCISMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL27627388 | 0.71 | PRKCI (0.63) | PRKCISMARCA2SMARCA4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131938-A1 | QUINAZOLINE COMPOUND AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2024-06-27 | — | — | WO | disclosed |
| WO-2023143135-A1 | QUINAZOLINE DERIVATIVE AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-08-03 | — | — | WO | disclosed |