Oxyquinoline

Oxyquinoline

SCHEMBL253313

Oc1cccc2cccnc12.Oc1cccc2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
MMP2 P08253 2/20 1.00
METAP2 P50579 2/20 1.00
CHRM1 P11229 1/20 1.00
COMT P21964 1/20 1.00
ADRA1A P35348 1/20 1.00
METAP1 P53582 1/20 1.00
HDAC8 Q9BY41 1/20 1.00
KDM4E B2RXH2 7/20 0.81
ALOX12 P18054 4/20 0.81
LMNA P02545 3/20 0.68
ALDH1A1 P00352 3/20 0.68
TDP1 Q9NUW8 3/20 0.61
MAPT P10636 2/20 0.61
TP53 P04637 2/20 0.61
ALOX15 P16050 2/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
CYP3A4 P08684 2/20 0.61
HIF1A Q16665 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL37189 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21875199 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21645991 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22553419 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22466317 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21195162 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL20703753 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068817-A1 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONALIZED NANOPARTICLES NORTHWESTERN UNIVERSITY (US) 2010-03-18 US claimed
EP-2092077-A2 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONLIZED NANOPARTICLES Northwestern University (US) 2009-08-26 EP claimed
WO-2008127414-A2 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONLIZED NANOPARTICLES NORTHWESTERN UNIVERSITY (US) 2008-10-23 WO claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed
CN-105828791-B Keratin fiber is shaped using carbonic ester 宝洁公司 2019-09-20 CN disclosed
CN-105828787-B Shaping keratin fibres using oxoacetic acids and/or derivatives thereof 宝洁公司 2019-07-26 CN disclosed
CN-105828657-B Utensil for shaping fibrous material 宝洁公司 2019-07-16 CN disclosed
CN-105828793-B Shaping keratin fibres using sugar 宝洁公司 2019-06-18 CN disclosed
CN-109169670-A 8-hydroxyquinoline zinc is preparing the purposes in disinfectant use in agriculture 青岛中达农业科技有限公司 2019-01-11 CN disclosed
CN-107106450-A Shaping keratin fibres using arabinose and ethylene carbonate 宝洁公司 2017-08-29 CN disclosed
CN-107106438-A Process for shaping keratin fibres 宝洁公司 2017-08-29 CN disclosed
CN-106577719-A Bactericide composite for preventing and controlling gingko leaf blight 广西大学 2017-04-26 CN disclosed
EP-2330653-A1 COMPOSITE ORGANIC ELECTROLUMINESCENT MATERIAL Idemitsu Kosan Co., Ltd. (JP) 2011-06-08 EP disclosed
US-7956529-B2 Organic electroluminescent color light-emitting apparatus with organic electroluminescent devices with adjusted optical distances between electrodes IDEMITSU KOSAN CO., LTD. (JP) 2011-06-07 US disclosed
US-20100068817-A1 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONALIZED NANOPARTICLES NORTHWESTERN UNIVERSITY (US) 2010-03-18 US disclosed
EP-2092077-A2 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONLIZED NANOPARTICLES Northwestern University (US) 2009-08-26 EP disclosed
WO-2008127414-A2 COLORIMETRIC DETECTION OF METALLIC IONS IN AQUEOUS MEDIA USING FUNCTIONLIZED NANOPARTICLES NORTHWESTERN UNIVERSITY (US) 2008-10-23 WO disclosed
US-6360564-B1 Sol-gel method of preparing powder for use in forming glass CORNING INCORPORATED 2002-03-26 US disclosed
US-6210078-B1 Methods for the in situ removal of a contaminant from soil SOUTHERN COMPANY SERVICES 2001-04-03 US disclosed
US-6069113-A GIVEN AMOUNT OF TERPENE, AN EMULSIFIER COMPRISING THE REACTION PRODUCT OF A TALL OIL FATTY ACID AND AN ALCOHOL AMINE, AND A COPPER COMPLEX; LESS TOXIC AND LESS FLAMMABLE LAPORTE WATER TECHNOLOGIES & BIOCHEM, INC. (US) 2000-05-30 US disclosed