Oxyquinoline

Oxyquinoline

SCHEMBL37189

Oc1cccc2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
MMP2 P08253 2/20 1.00
METAP2 P50579 2/20 1.00
CHRM1 P11229 1/20 1.00
COMT P21964 1/20 1.00
ADRA1A P35348 1/20 1.00
METAP1 P53582 1/20 1.00
HDAC8 Q9BY41 1/20 1.00
KDM4E B2RXH2 7/20 0.81
ALOX12 P18054 4/20 0.81
LMNA P02545 3/20 0.68
ALDH1A1 P00352 3/20 0.68
TDP1 Q9NUW8 3/20 0.61
MAPT P10636 2/20 0.61
TP53 P04637 2/20 0.61
ALOX15 P16050 2/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
CYP3A4 P08684 2/20 0.61
HIF1A Q16665 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL29365411 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL253313 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 1.00 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21875199 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21645991 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22553419 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22466317 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21195162 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL20703753 0.98 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 80460 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410766-B1 None US claimed
CN-122079813-A Neutral blocking remover, fluorine-containing symmetrical double-arm surfactant and preparation method thereof 2026-05-26 CN claimed
CN-119529194-B Macromolecular anticancer drug and preparation method of controllable molecular weight thereof TSINGHUA UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122080762-A Self-repairing polyurethane composition and preparation method thereof 2026-05-26 CN claimed
CN-122079884-A Method for treating acidic reaction liquid in 8-hydroxyquinoline production process 2026-05-26 CN claimed
US-12630443-B2 Nickel-cobalt-manganese ternary positive electrode material nanorod and use thereof GUANGDONG BRUNP RECYCLING TECHNOLOGY CO., LTD. (CN) 2026-05-19 US claimed
CN-115275338-B Electrolyte composition and secondary battery using same 台湾立凯电能科技股份有限公司 2026-05-19 CN claimed
CN-122054907-A Organic electroluminescent device and electronic equipment thereof 北京夏禾科技股份有限公司 2026-05-15 CN claimed
CN-122055338-A Method for analyzing Supplementary Cementitious Material (SCM) and predicting behavior of SCM in cementitious mixture 伊利诺伊大学董事会 2026-05-15 CN claimed
CN-122035843-A Spherical powder material and preparation method and application thereof 重庆锦添翼新能源科技有限公司 2026-05-15 CN claimed
US-3963419-A 8-HYDROXYQUINOLINE SUN OIL COMPANY OF PENNSYLVANIA (US) 1976-06-15 US claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US claimed
US-3951840-A CHELATING AGENT, INORGANIC PEROXIDE BLEACH KAO SOAP CO., LTD. (JA) 1976-04-20 US claimed
US-3950437-A PEROXY ACIDS, OXIDATION CATALYSTS OXIRANE CHEMICAL CO. (JA) 1976-04-13 US claimed
US-3944669-A 8-HYDROXY QUINOLINE DERIVATIVES PEPRO (FR) 1976-03-16 US claimed
US-3940470-A Direct recovery of metals from fluid anhydrous metal halides derived from marine nodule halidation DEEPSEA VENTURES, INC. (US) 1976-02-24 US claimed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US claimed
US-3931912-A Two-part hair dye or hair bleach package THE GILLETTE COMPANY (US) 1976-01-13 US claimed