Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467718 | 0.95 | CAPN1 (0.47) | SMN1; SMN2LMNASYKCTSSCTSL | |
| SCHEMBL30407162 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNASYKCTSSCTSL | |
| SCHEMBL25330859 | 0.89 | LMNA (0.63) | SMN1; SMN2LMNASYKMAPTMEN1 | |
| SCHEMBL25195645 | 0.89 | LMNA (0.63) | SMN1; SMN2LMNASYKMAPTMEN1 | |
| SCHEMBL29548496 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNASYKCTSSCTSL | |
| SCHEMBL29467638 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNASYKCTSSCTSL | |
| SCHEMBL23451336 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNASYKMAPTMEN1 | |
| SCHEMBL25372019 | 0.86 | LMNA (0.62) | SMN1; SMN2LMNASYKMAPTMEN1 | |
| SCHEMBL29467716 | 0.85 | HTT (0.53) | SMN1; SMN2LMNACTSSCTSLCAPN1 | |
| SCHEMBL24572425 | 0.85 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNASYKMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | SMN1; SMN2 4335/4885LMNA 493/4885SYK 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.