Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 6/20 | 0.69 |
| ▸ | OSBP | P22059 | 3/20 | 0.69 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.69 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.69 |
| ▸ | RORC | P51449 | 2/20 | 0.69 |
| ▸ | CRYAB | P02511 | 1/20 | 0.69 |
| ▸ | HMGCR | P04035 | 1/20 | 0.69 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.69 |
| ▸ | ITGAV | P06756 | 1/20 | 0.69 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333078 | 1.00 | NPC1L1 (0.69) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6393065 | 0.91 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6387538 | 0.91 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6392603 | 0.91 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6392359 | 0.91 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25336739 | 0.87 | NPC1L1 (0.67) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6389672 | 0.83 | PTPN1 (0.74) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL6389389 | 0.83 | NPC1L1 (0.64) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL23563231 | 0.82 | OSBP (1.00) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25333525 | 0.82 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789726-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023143398-A1 | STEROID AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |