Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.58 |
| ▸ | RELA | Q04206 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429836 | 0.91 | GRM7 (0.68) | TSHRALDH1A1NOTUMSMN1; SMN2GRM7 | |
| SCHEMBL25430592 | 0.90 | GRM7 (0.63) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL5070870 | 0.85 | TSHR (0.72) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL23723711 | 0.83 | TSHR (0.69) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL308295 | 0.83 | NOTUM (0.74) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL25428357 | 0.82 | ALDH1A1 (0.47) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL30557602 | 0.80 | NOTUM (0.56) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL1546073 | 0.79 | TSHR (0.77) | TSHRLMNACYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL31650229 | 0.78 | NOTUM (1.00) | TSHRL3MBTL1ALDH1A1NOTUMMAPT | |
| SCHEMBL2278917 | 0.78 | NOTUM (1.00) | TSHRL3MBTL1ALDH1A1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |