Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 7/20 | 0.70 |
| ▸ | OSBP | P22059 | 3/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.70 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.70 |
| ▸ | RORC | P51449 | 2/20 | 0.70 |
| ▸ | CRYAB | P02511 | 1/20 | 0.70 |
| ▸ | HMGCR | P04035 | 1/20 | 0.70 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.70 |
| ▸ | ITGAV | P06756 | 1/20 | 0.70 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.70 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.64 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333525 | 1.00 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL31504615 | 0.87 | NPC1L1 (0.61) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL23563231 | 0.83 | OSBP (1.00) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL22559541 | 0.83 | OSBP (1.00) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL20299556 | 0.83 | OSBP (1.00) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25035613 | 0.83 | OSBP (1.00) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25334817 | 0.83 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25333192 | 0.83 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25334814 | 0.83 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC | |
| SCHEMBL25333188 | 0.83 | NPC1L1 (0.70) | NPC1L1OSBPOSBP2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143398-A1 | STEROID AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |