Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337033 | 0.89 | EPHX2 (0.37) | EPHX2 | |
| SCHEMBL23289669 | 0.79 | JAK2 (0.42) | JAK2JAK1TYK2IRAK4IRAK1 | |
| SCHEMBL16057033 | 0.78 | ALDH1A1 (0.40) | JAK2JAK1TYK2IRAK4IRAK1 | |
| SCHEMBL22235919 | 0.75 | ALDH1A1 (0.38) | EPHX2 | |
| SCHEMBL25067443 | 0.74 | LRRK2 (0.41) | JAK2JAK1TYK2IRAK4 | |
| SCHEMBL27121655 | 0.73 | KDM5A (0.39) | JAK2JAK1TYK2IRAK4 | |
| SCHEMBL12800200 | 0.73 | IRAK4 (0.46) | JAK2JAK1TYK2IRAK4IRAK1 | |
| SCHEMBL24660447 | 0.73 | JAK2 (0.45) | JAK2JAK1TYK2IRAK4IRAK1 | |
| SCHEMBL31226852 | 0.73 | JAK1 (0.53) | JAK2JAK1TYK2IRAK4IRAK1 | |
| SCHEMBL21996625 | 0.72 | KDM5A (0.42) | JAK2JAK1TYK2IRAK4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143356-A1 | METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR FOR TREATING MTAP DELETION-TYPE CANCER | 勤浩医药（苏州）有限公司 | 2023-08-03 | — | — | WO | disclosed |