Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122101 | 1.00 | KCNH2 (0.36) | KCNH2CDC7CDK2MAPK8MAPK9 | |
| SCHEMBL25336908 | 0.79 | KCNH2 (0.36) | KCNH2CDC7CDK2MAPK8MAPK9 | |
| SCHEMBL987880 | 0.68 | P2RX3 (0.36) | KCNH2CDC7CDK2AR | |
| SCHEMBL17027091 | 0.67 | KCNH2 (0.49) | KCNH2CDC7CDK2ROCK1 | |
| SCHEMBL14136858 | 0.65 | PTK2 (0.44) | KCNH2CDC7CDK2MAOB | |
| SCHEMBL31591370 | 0.65 | PTK2 (0.44) | KCNH2CDC7CDK2MAOB | |
| SCHEMBL17026923 | 0.65 | KCNH2 (0.50) | KCNH2CDC7CDK2ROCK1DGAT1 | |
| SCHEMBL31239669 | 0.65 | AR (0.39) | AR | |
| SCHEMBL31122112 | 0.65 | HDAC11 (0.37) | KCNH2 | |
| SCHEMBL8547567 | 0.63 | BACE1 (0.46) | MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143354-A1 | TRICYCLIC COMPOUND AND APPLICATION THEREOF | 希格生科（深圳）有限公司 | 2023-08-03 | — | — | WO | disclosed |