Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 16/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338902 | 0.91 | EIF2AK4 (0.43) | EIF2AK4FLT3 | |
| SCHEMBL25339825 | 0.84 | FLT3 (0.42) | EIF2AK4FLT3 | |
| SCHEMBL25992534 | 0.84 | FLT3 (0.42) | EIF2AK4FLT3 | |
| SCHEMBL25988961 | 0.84 | FLT3 (0.42) | EIF2AK4FLT3 | |
| SCHEMBL25988962 | 0.84 | FLT3 (0.42) | EIF2AK4FLT3 | |
| SCHEMBL25338907 | 0.84 | EIF2AK4 (0.39) | EIF2AK4FLT3 | |
| SCHEMBL25989352 | 0.83 | FLT3 (0.45) | EIF2AK4FLT3 | |
| SCHEMBL25989354 | 0.83 | FLT3 (0.45) | EIF2AK4FLT3 | |
| SCHEMBL25993184 | 0.83 | FLT3 (0.45) | EIF2AK4FLT3 | |
| SCHEMBL25998222 | 0.83 | FLT3 (0.45) | EIF2AK4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150601-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-08-10 | — | — | WO | disclosed |